Health Condition 1: P599- Neonatal jaundice, unspecified
Conditions
Interventions
Intervention1: Phototherpay discontinuation threshold: Comparing phototherapy duration between two phototherapy discontinuation thresholds in greater than or equal to 35 weeks neonates with jaundice
I
Sponsors
Rashmi dandriyal
Eligibility
Inclusion criteria
Inclusion criteria: All hemodynamically stable breastfeeding neonates with gestation more than equal to 35 weeks and age less than 96 hours and serum bilirubin at or above phototherapy cut off as per AAP 2022 nomograms.
Exclusion criteria
Exclusion criteria: Total serum bilirubin at or above exchange threshold OR Neonates with features of acute bilirubin encephalopathy OR Neonates with hemolytic jaundice OR Neonate with G6PD deficiency or other inherited RBC disorder OR Perinatal asphyxia with HIE OR Sepsis screen positive or culture positive neonatal sepsis OR Babies having major congenital anomalies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of phototherapyTimepoint: Time duration between start and discontinuation of phototherapy | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of Rebound hyperbilirubinemia requiring reinstitution of phototherapyTimepoint: TSB concentration that reaches the phototherapy threshold within 72 hours of discontinuing phototherapy as per AAP 2022 nomogram.;TSB at rebound measurement (at 24 hours)Timepoint: TSB measured at 24 hours after phototherapy stopped.;Total length of hospital stayTimepoint: Time duration between birth and discharge from hospital;Incidence of exchange transfusion within 72 hours after discontinuing phototherapyTimepoint: The percentage of neonates requiring an exchange transfusion within 72 hours after discontinuing phototherapy (rebound hyperbilirubinemia.), due to a significant increase in TSB. | — |
Countries
India
Contacts
Public ContactRameshwar Prasad
AIIMS Patna
Outcome results
None listed