Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: Injection Amisulpride 5mg: at the time of induction
Control Intervention2: Injection Ondansetron 1mg/kg: 30 mins before the end of surgery
Sponsors
Swami Rama Himalayan Institute
Eligibility
Inclusion criteria
Inclusion criteria: ASA Physical status I or II Undergoing elective laparoscopic cholecystectomy willing to provide written informed consent
Exclusion criteria
Exclusion criteria: refusal to participate history of drug allergy to amisulpride or ondansetron pregnancy or gastroesophageal reflux disease history of cardiopulmonary diseases (asthma, COPD) Preoperative renal/hepatic dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. to evaluate the effectiveness of two antiemetics- ondansetron (1mg/kg) and amisulpride (5mg)- in controlling post operative nausea and vomiting after laparoscopic cholecystectomy -to assess hemodynamic fluctuations and the side effects of ondansetron and amisulpride -to assess the effectiveness of amisulpride and ondansetron preoperatively and postoperatively using quality of recovery 15 scoreTimepoint: 1. immediately after extubation 2. within 6 hours of extubation 3. within 12 hours of extubation 4. within 24 hours of extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| nilTimepoint: nil | — |
Countries
India
Contacts
Public ContactDr Veena Asthana
Himalayan institute of medical sciences
Outcome results
None listed