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Providing Vitamin D in children taking antiseizure medicines and children not on medication to find appropriate dose of Vitamin D to prevent deficiency

High dose vs low dose Vitamin D Supplementation in epileptic children taking anti-seizure medication: A Randomised Control Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096291
Enrollment
90
Registered
2025-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G403- Generalized idiopathic epilepsy and epileptic syndromes

Interventions

Intervention1: Vitamin D prophylaxis: High Dose Group: Supplemented with 2000 IU/day of Vitamin D to be given for 6 months Control Intervention1: Vitamin D prophylaxis: Low Dose Group: Supplemented w

Sponsors

JSS Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children between 1-18 years of age who are known cases of seizure disorder or newly diagnosed cases of epilepsy and taking any monotherapy antiseizure medication.

Exclusion criteria

Exclusion criteria: 1. Child is on polytherapy 2. Children suffering from inborn errors of metabolism

Design outcomes

Primary

MeasureTime frame
Prevalence of Vitamin D in both groups after 6 months of vitamin D supplementationTimepoint: Prevalence of Vitamin D in both groups after 6 months of vitamin D supplementation

Secondary

MeasureTime frame
1. To analyse occurrence of breakthrough seizures in both groups and role of Vitamin D in prevention of recurrence of seizures. 2. To analyse Ca, ionised Calcium, serum phosphate and alkaline phosphatase in both groups Timepoint: 6 months following start of Vitamin D, the patients are assessed for bone health and breakthrough seizures.

Countries

India

Contacts

Public ContactDr Chetak K B

JSS ACADEMY OF HIGHER EDUCATION

drchetak@gmail.com9844778712

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026