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Comparison of Probiotic, Ozonated Oil, and Conventional Calcium Hydroxide in Protecting Primary Teeth

Comparative Evaluation of Probiotic-Calcium Hydroxide Mix, Ozonated Coconut Oil-calcium hydroxide mix, and Conventional Calcium Hydroxide as a base in Indirect Pulp Capping of Primary Teeth: A Randomized controlled study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096286
Enrollment
105
Registered
2025-10-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Conventional Calcium Hydroxide: In this group, calcium hydroxide is mixed with saline to obtain a thick consistency suitable for placement. The prepared mix is applied as a protective b

Sponsors

MNR DENTAL COLLEGE AND HOSPITAL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children who are willing to participate in the study and informed consent was obtained from parents. CLINICAL CRITERIA Systemically healthy children of age 5-9 yrs with primary molars indicated for indirect pulp capping. Teeth with deep caries but vital pulp . RADIOLOGICAL CRITERIA: No history of swelling sinus tract or abscess. Intact periodontal ligament space. No evidence of internal or external root resorption. No periapical or furcal radiolucency

Exclusion criteria

Exclusion criteria: Children who are not willing to participate in the study. Teeth with spontaneous pain or signs of irreversible pulpitis. Presence of swelling sinus tract or abscess. Teeth with abnormal mobility unrelated to physiological exfoliation. Systemic conditions affecting wound healing or immunity. Presence of periapical or furcal radiolucency. Internal or external resorption detected. Presence of calcific degeneration or pulp obliteration.

Design outcomes

Primary

MeasureTime frame
Clinical and radiographic success of indirect pulp capping assessed by absence of pain, swelling, tenderness, mobility, and periapical/furcal radiolucency; evidence of dentin bridge formation.Timepoint: At follow-up visits — 3, 6, 9, and 12 months (CBCT at 12-month follow-up).

Secondary

MeasureTime frame
Evaluation of dentin bridge formation by assessing pulp vitality using clinical and CBCT assessment.Timepoint: At follow-up visits — 3, 6, 9, and 12 months (CBCT at 12-month follow-up).

Countries

India

Contacts

Public ContactDr NASEEMOON SHAIK

MNR DENTAL COLLEGE AND HOSPITAL

dr.naseemoonshaik@gmail.com8105935678

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026