Health Condition 1: P073- Preterm [premature] newborn [other]
Conditions
Interventions
Intervention1: Early Caffeine: Administration of Caffeine within one hour after birth
Control Intervention1: Routine caffeine: Administration of caffeine within one to three hours after birth
Sponsors
Dr Nishant Banait
Dr Anuja Bedekar
Eligibility
Inclusion criteria
Inclusion criteria: Preterm neonates born at less than 32 weeks gestational age admitted to NICU at AIIMS Nagpur within 3 hours after birth
Exclusion criteria
Exclusion criteria: 1. Parents and guardians unwilling to provide consent for the study 2. Major Congenital malformations 3. Severe perinatal asphyxia (Apgar score less than 3 at 10 minutes, requiring positive pressure ventilation for more than 10 minutes, requiring chest compressions)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of bronchopulmonary dysplasiaTimepoint: Requirement of supplemental oxygen at 36 completed weeks of gestational age | — |
Secondary
| Measure | Time frame |
|---|---|
| Requirement of invasive ventilationTimepoint: Requirement of invasive ventilation for more Tham initial 12 hours;Total number of days on mechanical ventilationTimepoint: till discharge;Total number of days on oxygen supportTimepoint: till discharge;Total duration of NICU stayTimepoint: till discharge;Postnatal steroid administrationTimepoint: till discharge;Echocardiographic parameters of systemic blood flowTimepoint: During initial 48 hours of life | — |
Countries
India
Contacts
Public ContactDr Anuja Bedekar
All India Institute of Medical Sciences, Nagpur
Outcome results
None listed