Comparison of two epidural adjuvants for endoscopic lumbar spine surgeries.

Evaluation of epidural ropivacaine with fentanyl and ropivacaine with dexmedetomidine for endoscopic lumbar spine surgery - NIL

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/096276

Enrollment

Registered

2025-10-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ropivacaine + Dexmedetomidine: 10 ml of 0.2% Ropivacaine with Dexmedetomidine at 0.4 mcg per ml of Ropivacaine administered in the epidural space at the time of induction of anaesthesi

Eligibility

Inclusion criteria

Inclusion criteria: i. Patients aged 18–65 years. ii. ASA physical status I–II. iii. Scheduled for elective endoscopic spine surgeries. iv. Provided informed consent.

Exclusion criteria

Exclusion criteria: 1. Known allergy to study drugs. 2. Coagulopathy or bleeding disorders. 3. Infection at the injection site. 4. Neurological or psychiatric illness. 5. Severe cardiorespiratory or renal disease.

Design outcomes

Primary

Measure	Time frame
Intra Operative PainTimepoint: 0( at time of induction), 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes, 240 minutes, 300 minutes, 360 minutes, and 12 hours.	—

Secondary

Measure	Time frame
1. Onset & duration of analgesia 2. Hemodynamic stability 3. Intraoperative pain 4. Sedation 5. Motor block assessment 6. Sensory block level 7. Degree of intraoperative cooperation 8. Need for rescue analgesiaTimepoint: 0 (at time of induction), 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes, 240 minutes, 300 minutes, 360 minutes, & 12 hours.	—

Measure

Time frame

1. Onset & duration of analgesia 2. Hemodynamic stability 3. Intraoperative pain 4. Sedation 5. Motor block assessment 6. Sensory block level 7. Degree of intraoperative cooperation 8. Need for rescue analgesiaTimepoint: 0 (at time of induction), 5 minutes, 10 minutes, 15 minutes, 20 minutes, 25 minutes, 30 minutes, 45 minutes, 60 minutes, 90 minutes, 120 minutes, 150 minutes, 180 minutes, 240 minutes, 300 minutes, 360 minutes, & 12 hours.

—

Countries

India

Contacts

Public ContactDr Meenu Chadha

Care CHL Hospital, Indore

chadha.meenu@gmail.com9977161035

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026