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Effectiveness of Intralipid Emulsion (fat solution) for the treatment of severe aluminium phosphide poisoning patients (a fumigant used for stored grains).

Efficacy of intralipid emulsion in severe aluminium phosphide poisoning: a randomised controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096271
Enrollment
84
Registered
2025-10-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T608- Toxic effect of other pesticides

Interventions

Intervention1: Intervention Group: Standard treatment: Patient will be resuscitated, including care of airway, breathing, and circulation. Intravenous fluids and vasopressors (Norepinephrine) will be

Sponsors

Dr Upendra Hansda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: History of aluminum phosphide poisoning. The suggestive clinical manifestations follow shortly after a single exposure to aluminum phosphide. Patients classified as severe poisoning as per the Poison Severity Score,

Exclusion criteria

Exclusion criteria: a) Patients with a history/clinical features of any poisoning other than aluminum phosphide or any associated poisoning with aluminum phosphide. b) Allergy to egg/soybean

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of Intralipid emulsion for reducing the mortality of aluminium phosphide-intoxicated patientsTimepoint: At 0 hour, 1 hour, 2 hour, 6 hour, 12 hour, 18 hour, 24 hour, 36 hour, 48 hour, 72 hour.

Secondary

MeasureTime frame
1. To evaluate the efficacy of Intralipid emulsion in reducing the ventilatory requirement in patients with severe aluminum phosphide poisoning. 2. To evaluate the efficacy of Intralipid emulsion in reducing the vasopressor requirement in patients with severe aluminum phosphide poisoning. 3. To evaluate the efficacy of Intralipid emulsion in reducing the length of hospital stay in severe aluminum phosphide poisoning patients.Timepoint: At 0 hour, 1 hour, 2 hours, 6 hours, 12 hours, 18 hours, 24 hours, 36 hours, 48 hours, 72 hours.

Countries

India

Contacts

Public ContactDr Athulya Sasidharan

AIIMS Bhubaneswar

uhansdah@gmail.com9437365720

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026