None listed
Conditions
Interventions
Intervention1: probitics capsules (brand name:prebo): each capsule contains probiotics bacteria of
1.bifidobacterium bifidum 150 million
2.bifidobacterium longum 150 million
3.streptococcus thermophi
Sponsors
DrMoulisbabu
Eligibility
Inclusion criteria
Inclusion criteria: Adults aged more than or equal to 18 years. BMI more than or equal 25 (obese as per Asian criteria) or waist circumference more than 102cm in male,more than 88cm in female. Prediabetes (defined as Fasting Blood Glucose 100–125 milligram per decilitre or Post prandial glucose 140-200milligram per decilitre or HbA1c 5.7–6.4.
Exclusion criteria
Exclusion criteria: 1.Patient on steroids, OCP, antibiotic intake (1 week). 2.Current or recent (past 3 months) probiotic/prebiotic supplementation. 3.Chronic diarhoea. 4.Pregnancy or lactation. 5.Severe hepatic, renal, or cardiac illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in insulin sensitivity as measured by HOMA-IR index.Timepoint: fasting insulin level checked at begining of the study ie sample collected at day 0 and at the end of the study ie once the patiet complete 90 days of probiotic course | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)fasting blood glucose 2)serum insulin level 3)lipid profileTimepoint: checked at begining of the study and at the end of the study | — |
Countries
India
Contacts
Public ContactMoulisbabu
pondicherry institute of medical sciences
Outcome results
None listed