Use of dexmeditomidine with lignocaine in controlling hemodynamic response in laryngoscopy and intubation

Comparison of two different doses of dexmeditomidine with lignocaine in controlling the hemodynamic response of laryngoscopy and intubation:A double blind randomized control trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/096208

Enrollment

Registered

2025-10-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: 0.5mcg Dexmeditomedine and Lignocaine 1.5mg/kg: 0.5mcg Dexmeditomedine and Lignocaine 1.5mg/kg Control Intervention2: 0.75mic Dexmeditomedine and Lignocaine 1.5mg/kg: 0.75mic De

Eligibility

Inclusion criteria

Inclusion criteria: ASA 1&2 weight 50-80kgs mallampatti 1&2

Exclusion criteria

Exclusion criteria: patient refusal patient who require more than 1 attempt of intubation anticipated difficult intubation associated comorbidities coagulopathy and neuromuscular diseases

Design outcomes

Primary

Measure	Time frame
compare HR after Laryngoscopy and intubationTimepoint: 0min, 2,4,6,8,10 mins following intubation	—

Secondary

Measure	Time frame
to compare SBP,DBP, and RPP following intubation. compare sedation using Ramsay sedation score, any complications or side effects if anyTimepoint: 0,2,4,6,8,10 mins	—

Countries

India

Contacts

Public ContactDr Basant Kumar dindor

R.n.t. medical college udaipur rajasthan

basant_17@yahoo.com9602237852

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026