This study focuses on helping oral cancer patients recover faster using the Enhanced Recovery After Surgery (ERAS) program. ERAS features evidence-based practices like improved pre-surgery nutrition, shorter fasting, better pain management, and early movement and feeding post-surgery

Implementing ERAS protocol in oral cancer patients undergoing free flap reconstruction: an experimental prospecting study - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Observational

Source

CTRI

Registry ID

CTRI/2025/10/096205

Enrollment

172

Registered

2025-10-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx

Interventions

Intervention1: experimental prospective cohort study: • Preoperative Assessment: o Baseline demographic data: Age, sex, BMI, smoking status, alcohol use. o Oral Cancer Staging: Record the T, N, and M

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients diagnosed with oral cavity cancer requiring free flap reconstruction as part of surgical management. Patients undergoing primary surgical resection and immediate reconstruction using microvascular free flap (e.g., radial forearm, fibula, or anterolateral thigh flap). Patients who are clinically fit for major surgery under general anesthesia. Patients willing to participate and provide written informed consent for inclusion in the study.

Exclusion criteria

Exclusion criteria: o Patients with a history of previous major reconstructive surgery of the oral cavity. o Patients with severe comorbidities (e.g., advanced heart failure, chronic renal failure, uncontrolled diabetes) that would significantly impact surgical or recovery outcomes. o Pregnancy or lactating women.

Design outcomes

Primary

Measure	Time frame
Length of hospital stay (LOS)Timepoint: o1 week: Clinical check for flap viability, wound healing, and complications. o1 month: Assessment of functional recovery (e.g., speech, swallowing, nutrition). o3 months: Evaluation of long-term recovery, recurrence, and psychosocial impact.	—

Secondary

Measure	Time frame
• Postoperative complications (e.g., flap failure, wound infection, sepsis, pneumonia). • Pain scores postoperatively, with a focus on the reduction in opioid use (). • Functional recovery outcomes such as speech, swallowing, & mobility. • Patient satisfaction: Assessed using validated questionnaires (e.g., EQ-5D, PROMIS). • Nutritional status: Preoperative vs. postoperative (tracked via serum albumin, weight changes, & dietary intake). Timepoint: o 1 week: Clinical check for flap viability, wound healing, & complications. o 1 month: Assessment of functional recovery (e.g., speech, swallowing, nutrition). o 3 months: Evaluation of long-term recovery, recurrence, & psychosocial impact.	—

Measure

Time frame

• Postoperative complications (e.g., flap failure, wound infection, sepsis, pneumonia). • Pain scores postoperatively, with a focus on the reduction in opioid use (). • Functional recovery outcomes such as speech, swallowing, & mobility. • Patient satisfaction: Assessed using validated questionnaires (e.g., EQ-5D, PROMIS). • Nutritional status: Preoperative vs. postoperative (tracked via serum albumin, weight changes, & dietary intake). Timepoint: o 1 week: Clinical check for flap viability, wound healing, & complications. o 1 month: Assessment of functional recovery (e.g., speech, swallowing, nutrition). o 3 months: Evaluation of long-term recovery, recurrence, & psychosocial impact.

—

Countries

India

Contacts

Public ContactDr Suanayana sarkar

Mahamana Pandit Madan Mohan Malaviya Cancer Centre, Varanasi

draseemmishra@gmail.com08080611946

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026