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A study to find out whether age affects how well pulse pressure variation predicts the body's response to fluids

Comparing the reliability of pulse pressure variation in assessing fluid responsiveness between younger and older adult population. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/10/096190
Enrollment
122
Registered
2025-10-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Intervention4: Nil: Nil

Sponsors

Jawaharlal Institute of Post Graduate Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients over 18 years of both genders of American Society of Anaesthesiologists status ASA 1,2,3 requiring arterial line during surgery under general anesthesia

Exclusion criteria

Exclusion criteria: Patients with LV systolic dysfunction Patients with Grade 3 diastolic dysfunction Patients with arrhythmias Patients who are on vasopressor support

Design outcomes

Primary

MeasureTime frame
To compare the proportion of population falling in grey zone between younger and older population.Timepoint: determined after fluid challenge—

Secondary

MeasureTime frame
To find out optimal cut off of PPV in younger and older adult populationTimepoint: baseline and after fluid challenge;To compare mean carotid intima medial thickness between younger and older adultsTimepoint: baseline;To compare the common carotid arterial compliance measured between younger and older adults.Timepoint: baseline;To note percentage change in EtCO2 after fluid challengeTimepoint: baseline and after fluid challenge—

Countries

India

Contacts

Public ContactSowmya K

Jawaharlal Institute of Postgraduate Medical Education and Research

jipmervasu@gmail.com9894444102

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026