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Efficacy of coconut oil aloe vera mouth rinse on radiation-induced xerostomia among head and neck cancer patients.

Effectiveness of coconut oil aloe vera mouth rinse on radiation-induced xerostomia among head and neck cancer patients. - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096186
Enrollment
82
Registered
2025-10-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C14- Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx

Interventions

Intervention1: Coconut oil Aloevera Mouth rinse: This study involves an intervention where participants in the experimental group are administered with coconut oil aloe vera mouth rinse (1:1 ratio) fo

Sponsors

Ms Chinthaja J
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Cancer patients who: 1. Have received external radiation therapy targeting the head and neck areas, with a minimum of four sessions. 2. Experience mild xerostomia (scores one to three) to moderate xerostomia (scores four to six) after radiation therapy.

Exclusion criteria

Exclusion criteria: Cancer patients who: 1. Have a history of xerostomia before receiving radiation therapy. 2. Are allergic to coconut oil or aloe vera. 3. Experience difficulty in performing mouth rinsing. 4. Have undergone oral surgery recently. 5. Have any systemic diseases that reduce or suppress salivation. 6. Are using medications known to suppress salivation.

Design outcomes

Primary

MeasureTime frame
Reduction in severity of xerostomia measured using Challacombe Oral Dryness Scale and subjective symptoms using Groningen Radiation-Induced Xerostomia (GRIX) Questionnaire.Timepoint: Baseline (Day 0), alternate days up to Day 7

Secondary

MeasureTime frame
Safety of using coconut oil aloe vera mouth rinse Association between the severity of xerostomia with selected clinical variablesTimepoint: Day 0 and Day 7

Countries

India

Contacts

Public ContactMr. HARISH DEYANNAVAR

Nitte Usha Institute of Nursing Sciences

harish.deyannavar@nitte.edu.in8050507699

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026