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A study to compare the pain relief from two radiofrequency nerve treatments-3nerve vs 5 nerve- in people with long term knee osteoarthritis

Comparison of the efficacy of 3 point versus 5 point genicular nerve radiofrequency ablation in patients with chronic knee osteoarthritis: A randomized control study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096137
Enrollment
60
Registered
2025-10-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: 5 nerve Radiofrequency Ablation: thermal lysis of the sensory nerves supplying the knee joint,using a probe of temperature 80-90 degree celcius for a duration of 90 seconds thereby disr

Sponsors

lady hardinge medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age group of 40 to 75 years 2. Knee osteoarthritis confirmed by X ray (Kellgren-Lawrence grade 2-4) with pain for at least 3 months and pain intensity of 4 on Numerical Rating Scale (NRS) despite conservative management 3.Patients refusing surgery 4. Positive response to diagnostic genicular nerve block (more than 50 percent pain reduction)

Exclusion criteria

Exclusion criteria: 1. Previous knee surgery or knee joint replacement or traumatic knee injury 2. Inflammatory arthritis such as rheumatoid arthritis, gout and psoriatic arthritis 3. Patellofemoral osteoarthritis 4. Patients receiving any other invasive treatment for knee osteoarthritis during the study period 5, Prior radiofrequency treatment of the target knee

Design outcomes

Primary

MeasureTime frame
To compare the efficacy of 3-point versus 5-point genicular nerve radiofrequency ablation in terms of functional improvement by Oxford Knee Score in patients with chronic knee osteoarthritis at three months post-procedure.Timepoint: 1 week, 1 month and 3 months, months post-procedure

Secondary

MeasureTime frame
Pain reduction by Numerical Rating Scale at 1 week, 1 month, and 3 months post-procedure 2. Procedure-related adverse events and complications Timepoint: 1 week, 1 month and 3 months, months post-procedure

Countries

India

Contacts

Public ContactGanesh S Nath

lady Hardinge Medical college

nhayaran97@gmail.com9873903603

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026