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Benefits of early laser in CSCR

Visual functions after early laser in Central Serous Chorioretinopathy - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096126
Enrollment
30
Registered
2025-10-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H537- Vision sensitivity deficiencies

Interventions

Intervention1: Focal Laser: ND-YAG 532nm laser is used to treat area of leakage as identified on dye based angiography Follow up will be 2 monthly intervals for a period of 6 months Control Interventi

Sponsors

Hyderabad Eye Research Foundation, L V Prasad Eye Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients presenting with first episode of acute CSCR as diagnosed on OCT with presence of subretinal fluid involving foveal centre with duration of symptoms less than 4 weeks will be included.

Exclusion criteria

Exclusion criteria: 1. SRF secondary to cause other than CSCR 2. History suggestive of previous episodes of CSCR (Also by clinical signs or investigations) 3. Presence of CNVM with CSCR 4. Hazy media due to cataracts/ any other cause not allowing detailed imaging 5. Previous history of Anti VEGF/ Laser photocoagulation 6. Presence of cystic macular edema or subretinal exudates associated ocular comorbidities 7. Any allergy/ systemic contraindication to use of FFA/ICGA dyes or laser.

Design outcomes

Primary

MeasureTime frame
1.Effect of laser on higher-order visual functions following fluid resolution. Key vision metrics analysed: 2.BCVA 3.Contrast Sensitivity Colour Vision 4.Metamorphopsia 5.Aniseikonia Timepoint: 2, 4 and 6 months

Secondary

MeasureTime frame
Proportion of patients achieving fluid resolution in each arm. Number of crossovers (patients transitioning from observation to laser). ICGA findings for non-resolving CSCR cases. Comparison of change in OCT parameters to microperimetry changes Timepoint: 2, 4 and 6 months

Countries

India

Contacts

Public ContactDrRitesh Narula

L V Prasad Eye Institute

ritesh.narula@lvpei.org9711857437

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026