Silver or Not? The impact of nanoparticles dressings on Wound recovery and Patient experience following periodontal flap surgery

Silver or Not? The impact of nanoparticles dressings on Wound recovery and Patient experience following periodontal flap surgery :A double blinded Randomised clinical trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/096124

Enrollment

Registered

2025-10-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis Health Condition 2: Z729- Problem related to lifestyle, unspecified

Interventions

Intervention1: Silver nanoparticle membrane (acticoat) with Coe pak: Periodontal dressings incorporated silver nanoparticles (AgNPs), which are particles of silver smaller than 100 nm with potent anti

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 30-55 years Good systemic condition Non smokers Chronic periodontitis subjects (with pocket depth more than or equal to 5mm), requiring periodontal flap surgery

Exclusion criteria

Exclusion criteria: Poor oral hygiene (Plaque score and Bleeding on probing more than 25 precent) Uncontrolled diabetes mellitus. Immune diseases. Heavy smokers Bruxism. History of allergy to silver Presence of any active periodontal diseases, immunocompromised condition, and steroid medication.

Design outcomes

Primary

Measure	Time frame
Landry wound healing indexTimepoint: 1 week	—

Secondary

Measure	Time frame
Plaque index Colony forming units(Microbilogical) IQ ELISA (Biochemical VEGF marker) VAS ScoreTimepoint: 1 week	—

Countries

India

Contacts

Public ContactDr Shambhavi

AIIMS Rishikesh

visit.shambhavi0423@gmail.com8789980178

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026