Skip to content

Comparing the Effects of Sharbat Khaksi versus Paracetamol in Children with Typhoid Fever Who Are Also Receiving Antibiotic Treatment.

Therapeutic Evaluation of Sharbat Khaksi and Cefixime vs Paracetamol and Cefixime in Pediatric Typhoid Fever: A Randomized Parallel Arm Open Label Interventional Clinical Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096099
Enrollment
70
Registered
2025-10-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: A010- Typhoid fever

Interventions

Intervention1: Sharbat Khaksi and Cefixime: The patients will be given Sharbat Khaksi (as per body weight which is less than or equall to 15 kg is 5ml, more than 15 kg to less than or equall to 23 kg

Sponsors

Dr Sudhanshu
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: A history of fever and presentation for more than or equals to 72 hours and a documented fever [99.5 degree fahrenheit to 102 degree fahrenheit (axillary)]. Cases of positive Blood culture of S typhi Patients whose parents or guardian or LAR will give consent and able to do follow-up.

Exclusion criteria

Exclusion criteria: Patients who had received intravenous or oral antibiotics before getting Blood culture of S typhi. Clinically diagnosed cases of malaria and dengue. Patients with known other systemic disease. Previous history of hypersensitivity to any of the trial drugs. Complicated typhoid fever cases suffers from melena, severe abdominal discomfort, hepatic encephalopathy. Any concomitant treatment like anti-depressants or anticonvulsants

Design outcomes

Primary

MeasureTime frame
Fever clearance time (FCT)Timepoint: 14 days

Secondary

MeasureTime frame
Improvement in other Subjective parametersTimepoint: 14 days

Countries

India

Contacts

Public ContactDr Md Sohail

State Unani Medical College and Hospital Himmatganj Prayagraj

shlt869@gmail.com8279944096

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026