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COMPARISON OF SLOW AND RAPID TOURNIQUET RELEASE ON BRAIN PRESSURE MEASURED BY OPTIC NERVE IN PATIENTS UNDERGOING LOWER LIMB SURGERY

COMPARISON OF GRADUAL AND RAPID TOURNIQUET DEFLATION ON INTRACRANIAL PRESSURE MEASURED BY OPTIC NERVE SHEATH DIAMETER IN PATIENTS UNDERGOING LOWER LIMB ORTHOPEDIC SURGERY UNDER SPINAL ANAESTHESIA - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096092
Enrollment
70
Registered
2025-10-15
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Gradual tourniquet deflation: Gradual tourniquet deflation done on patient undergoing lower limb orthopaedic surgery Control Intervention1: Rapid tourniquet deflation: Rapid tourniquet

Sponsors

Vardhman Mahavir Medical College and Safdarjung Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult patient (18-65 years) ASA GRADE 1/2 UNDERGOING ELECTIVE LOWER LIMB ORTHOPEDIC SURGERIES USING TOURNIQUET UNDER SPINAL ANAESTHESIA

Exclusion criteria

Exclusion criteria: 1. Patients with pre-existing neurological disorder such as brain tumour, hydrocephalus etc. 2. Cardiopulmonary disease influencing cerebral haemodyanamic such as uncontrolled hypertension, heart failure etc. 3. Patients with eye disease: external trauma to eye, optic neuritis, optic nerve trauma, previous eye surgery 4.Coagulopathy or patient on anticoagulant therapy, local site infection contraindicating spinal anaesthesia

Design outcomes

Primary

MeasureTime frame
To compare the effect of rapid and gradual tourniquet deflation on increase in intracranial pressure changes,measured by optic nerve sheath diameter in patients undergoing lower limb orthopaedic surgeries under spinal anaesthesia.Timepoint: ONSD measurement at 15 minutes before spinal anaesthesia,before tourniquet deflation, and at 1 min 5 min 10 min and 15 min after deflation—

Secondary

MeasureTime frame
To compare the effect of rapid & gradual tourniquet deflation on end tidal CO2 in patient undergoing lower limb orthopedic surgery under spinal anaesthesiaTimepoint: Before tourniquet deflation, 1 min, 5 mins, 10 mins & 15 mins after deflation;Effect of rapid & gradual tourniquet deflation on blood pressure (SBP,DBP,MAP) & heart rateTimepoint: Before spinal anaesthesia, at 1 min, 5 mins,10 mins,15 mins after tourniquet deflation—

Countries

India

Contacts

Public ContactDr Dimple Pande

Vardhman Mahavir Medical College and Safdarjung Hospital

drdimplepande@gmail.com98684355534

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026