Health Condition 1: M171- Unilateral primary osteoarthritisof knee Health Condition 2: M171- Unilateral primary osteoarthritisof knee
Conditions
Interventions
Intervention1: Dextrose-prolotherapy and ozone: Group B (Prolotherapy Group): will receive 3 doses of 10 ml of 25 % dextrose, in a 2-week interval
Group C (Ozone Group): will receive 3 doses of 10 ml
Sponsors
AIIMS Kalyani
Eligibility
Inclusion criteria
Inclusion criteria: 1. Clinically diagnosed as an OA knee according to the American College of Rheumatology (ACR) criteria 2. Radiographic Kellgren-Lawrence grades2 and 3 3. Knee pain with pain intensity of more or equal to 4 of 10 on a visual analoguescale,most days for at least 3 months, refractory to conservative treatments
Exclusion criteria
Exclusion criteria: 1. Severe neurological or psychiatric diseases 2. History of any steroid injection within 3 months 3. Previous knee surgeries (unicompartmental or total arthroplasty, debridement arthroscopy, osteotomies) 4. Persons using anticoagulants or with bleeding disorders 5. Persons with uncontrolled diabetes and hypertension 6. Any history of allergy or superficial skin infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scaleTimepoint: At baseline, after 1month, after 4 month and after 6 month | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis IndexTimepoint: 1 months, 4 months and 6 months;Oxford knee scoreTimepoint: 1 months, 4 months, 6 months | — |
Countries
India
Contacts
Public ContactSouvik Bhattacharjee
AIIMS Kalyani
Outcome results
None listed