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Are children and adolescents living with nephrotic syndrome at higher risk for developing hypertension ?

Profile of Continuous ambulatory blood pressure monitoring in children and adolescents with nephrotic syndrome - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/10/096081
Enrollment
40
Registered
2025-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N04- Nephrotic syndrome

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

Dr Mukta Mantan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All children and adolescents detected with steroid sensitive or steroid resistant nephrotic syndrome having the disease for at least last two years and are in partial or complete remission

Exclusion criteria

Exclusion criteria: 1. Children with eGFR less than 60 ml per min per 1.73 meter squares. 2. Children diagnosed with diabetes mellitus, familial hyperlipidemia syndromes, stage 2 or more of hypertension. 3. Children with nephrotic syndrome who had infrequently relapsing course throughout.

Design outcomes

Primary

MeasureTime frame
Determination of mean systolic, diastolic blood pressures during day and night time using continuous ambulatory blood pressure monitor for detection of hypertension or masked hypertension. Identifying systolic and diastolic loads over a 24 hours period and nocturnal dipping in study population.Timepoint: baseline and for next 24 hours

Secondary

MeasureTime frame
Association of hypertension with duration, type & treatment (dosage & duration of steroids, calcineurin inhibitors, antihypertensives) of nephrotic syndrome. Proportion of patients with left ventricular hypertrophy.Timepoint: baseline

Countries

India

Contacts

Public ContactDr Shrishti Rai

Maulana Azad Medical College

muktamantan@hotmail.com9968604315

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026