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A study to assess the effect of transcranial direct current stimulation with baclofen on muscle tightness and movement in stroke patients

Combined Effects of Transcranial Direct Current Stimulation and Oral Baclofen on Spasticity and Motor Function in Patients with Spastic Hemiplegia: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/096061
Enrollment
36
Registered
2025-10-14
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G811- Spastic hemiplegia

Interventions

Intervention1: Transcranial direct current stimulation , oral Baclofen and Conventional physiotherapy: The subjects will be given detailed information about the Transcranial direct current stimulation

Sponsors

KLE Academy of Higher Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with : All genders between the age group of 18 to 65 years of age, Who are willing to participate Diagnosed with first time stroke Ischemic or Hemorrhagic (more than 3months) Spasticity more than 1 plus according to Modified Ashworth Scale in atleast one major upper or lower limb muscle. Consciousness able to follow verbal commands & no hearing disability No other associated traumatic and non traumatic disorder of neurological, musculoskeletal and cardiac system

Exclusion criteria

Exclusion criteria: Subjects with Severe cognitive impairment Known Allergy or intolerance to Oral Baclofen drug Pregnancy or lactation Sensory disturbances History of seizures or epilepsy Presence of metal implants or electronic devices ( eg: pacemaker, cochlear implants) Currently receiving other spasticity reducing treatment (eg: botulinum toxin , intrathecal baclofen) Other unstable medical conditions

Design outcomes

Primary

MeasureTime frame
Modified Ashworth Scale Fugl meyer assessment Scale Timepoint: Modified Ashworth Scale to assess spasticity pre and post 2 week intervention Fugl meyer assessment Scale is used to assess motor function pre and post intervention

Secondary

MeasureTime frame
Stroke Impact ScaleTimepoint: Stroke Impact scale assesses physical function , emotion , memory, communication and social participation in stroke survivors pre and post intervention.

Countries

India

Contacts

Public ContactIsha shah

KAHER Institute of Physiotherapy

raghavendrasingh@klekipt.edu.in9886288225

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026