Health Condition 1: P220- Respiratory distress syndrome of newborn
Conditions
Interventions
Intervention1: Bubble CPAP (Variable flow CPAP system.): In this mode, continuous positive airway pressure is delivered to the preterm infant through a bubble CPAP circuit. The expiratory limb of the
Sponsors
AIIMS Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: Preterm (less than 37 completed weeks at birth) who develop early onset respiratory distress requiring CPAP within 6 hours of birth.
Exclusion criteria
Exclusion criteria: 1. Surgical anomalies of chest and abdomen 2. Syndromic newborns 3. Preterm infants who require delivery room intubation and early surfactant replacement therapy. 4. Perinatal asphyxia with encephalopathy or cord pH 5. Pneumothorax or air-leaks prior to enrolment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.CPAP failure in the first 72 hours of birth 2.Need of mechanical ventilation 3.Incidence of hypoxic respiratory failure Timepoint: baseline data, 1 day, 3 days. 7 days, 14 days and 28 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Duration of respiratory support. 2.Need for surfactant replacement therapy 3.Need of vasopressors in first 72 hours 4.Oxygenation assessment by Spo2/Fio2 for the first 72 hours after birth. 5.Incidence of common preterm morbidity like BPD, IVH, PDA,ROP,NEC, ect. 6.Incidence of complications of nasal trauma & air leaks. 7.Duration of oxygen supplementation. Timepoint: baseline, 1 day, 3 days, 7 days, 14 days & 28 days | — |
Countries
India
Contacts
Public ContactDr Chetan Khare
AIIMS Bhopal
Outcome results
None listed