Health Condition 1: J17- Pneumonia in diseases classified elsewhere
Conditions
Interventions
Intervention1: BIS: The bispectral index (BIS) is an objective measure for evaluating levels of awareness, frequently employed as an anaesthetic tool, with its use also expanding to the intensive care
Sponsors
Department of Critical Care Medicine
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age 18 to 65 years and Mechanically ventilated for more than 48 hours. 2.Patients/ Parents/ Caregivers who are willing to give informed consent 3.Patients with renal and hepatic disorder for subgroup analysis.
Exclusion criteria
Exclusion criteria: 1. Head injuries 2. Required Deep (Barbiturate Coma) Sedation for Status Epilepticus. 3.Patients known to have any focal brain disease or abnormal electrical brain activities such as epilepsy .
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity , Specificity, Positive predictive & negative predictive values of BIS and clinical sedation scales. Correation between BIS and RASS. Timepoint: every 4 hourly till extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Whether BIS monitoring can reduce sedative dose requirements while preventing undersedation events.Timepoint: total volume in ml of drug infused in the 24 h study period;. | — |
Countries
India
Contacts
Public ContactDr Sathya Narayanan K
Bangalore Medical College and Research Institute, Bangalore - BANGALORE
Outcome results
None listed