Health Condition 1: G409- Epilepsy, unspecified
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Intervention4: Nil: Nil
Sponsors
Indian Society of Critical Care Medicine
Eligibility
Inclusion criteria
Inclusion criteria: Patients with refractory status epilepticus unresponsive to first line and two second line intravenous antiepileptics and requiring anesthetic medications to control seizures
Exclusion criteria
Exclusion criteria: 1.Known, suspected history of malignant hyperthermia 2.Patients with severe acute respiratory distress syndrome and arterial oxygen tension to inspired oxygen concentration ratio less than 100 requiring inverse ratio ventilation or prone ventilation 3.Patients with diagnosis of Mitochondrial disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the levels of serum NSE and IL-10 between patients receiving isoflurane and midazolam for treatment of RSETimepoint: At baseline before starting the drug and after stopping the drug (isoflurane or midazolam) | — |
Secondary
| Measure | Time frame |
|---|---|
| In hospital mortality & Glasgow outcome scale extendedTimepoint: At discharge & 6 months after discharge | — |
Countries
India
Contacts
Public ContactDR SONIA BANSAL
NIMHANS
Outcome results
None listed