Comparison of Lignocaine with Adrenaline and Ropivacaine Combination versus Ropivacaine alone for Nerve Block in Hand and Forearm Surgeries

Comparison of Block Characteristics of An Equal Mixture of 2% Lidocaine with Adrenaline And 0.5% Ropivacaine Versus 0.5% Ropivacaine Alone for Ultrasound Guided Axillary Brachial Plexus Block: A Double-Blinded Randomised Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/095925

Enrollment

Registered

2025-10-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S62- Fracture at wrist and hand level Health Condition 2: S52- Fracture of forearm

Interventions

Intervention1: Equal Mixture of 2% Lidocaine with Adrenaline and 0.5% Ropivacaine for Axillary brachial plexus block: Total volume with dose of 0.4ml/kg of an Equal Mixture of 2% Lidocaine with Adrena

Eligibility

Inclusion criteria

Inclusion criteria: Adult patients (18-65 years) in need of upper limb anaesthesia for undergoing orthopaedic surgeries at elbow and below under axillary brachial plexus block. American Society of Anaesthesiologists I and II physical status. Body weight within BMI less than or 30 kg/m²

Exclusion criteria

Exclusion criteria: Allergy to local anesthetics. Pre-existing neuropathy or brachial plexus injury. Coagulopathy or anticoagulant use. Pregnancy or lactation. Patient refusal. Known case of Renal failure. Known case of Hepatic failure. Evidence of infection at axillary area Patients unable to abduct the operative arm Patients receiving general anaesthesia

Design outcomes

Primary

Measure	Time frame
Comparison of ONSET TIME of complete conduction blockade in both the groups (defined in minutes, as the time from end of needling to the time required to reach a minimum score of 14/16 using a sensorimotor composite scale.)Timepoint: at regular intervals of 2 minutes, till a composite sensorymotor score of 14/ 16 is achieved	—

Secondary

Measure	Time frame
Durantion of Sensory Block Timepoint: Defined in hours, as the time from inability to perceive cold sensation when tested with an alcohol swab to the point where patient first reported return of pain/itching/other sensation;Duration of motor blockTimepoint: defined in hours,as the tume from inability to perform specific voluntary motor functions of upper limbs like wrist flexion or extension/ thumb adduction/ elbow flexion to the point where first voluntary movements are observed.;Success rate of block (need for supplementation or conversion to general Anaesthesia)Timepoint: inability to achieve a composite sensorymotor score of less than 14 in 30 mins.;To assess any adverse effectsTimepoint:	—

Measure

Time frame

Durantion of Sensory Block Timepoint: Defined in hours, as the time from inability to perceive cold sensation when tested with an alcohol swab to the point where patient first reported return of pain/itching/other sensation;Duration of motor blockTimepoint: defined in hours,as the tume from inability to perform specific voluntary motor functions of upper limbs like wrist flexion or extension/ thumb adduction/ elbow flexion to the point where first voluntary movements are observed.;Success rate of block (need for supplementation or conversion to general Anaesthesia)Timepoint: inability to achieve a composite sensorymotor score of less than 14 in 30 mins.;To assess any adverse effectsTimepoint:

—

Countries

India

Contacts

Public ContactSushil Krishnan

Northern Railway Central Hospital, New Delhi

dr.sushilkrishnan@gmail.com9717630552

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026