Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group Nefopam: Patients will receive 8 ml of 0.125 percentage of Bupivacaine containing 5 mg of Nefopam epidurally at the end of surgery
Control Intervention1: Group Tramadol: Patients
Sponsors
Vinayak Missions Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1) ASA physical status I and II 2) Patients scheduled for lower abdominal surgeries 3) Patients capable of providing informed written consent and understanding pain assessment instruction 4) Body Mass Index less than 35 kg per metre square
Exclusion criteria
Exclusion criteria: 1) Patient refusal 2) Contraindication to neuraxial anaesthesia 3) History of significant cardiovascular, respiratory, hepatic or renal dysfunction 4) Known hypersensitivity to study medications 5) History of chronic pain or regular analgesic medication use 6) Psychiatric disorders or inability to comprehend pain assessment tools 7) Pregnancy or Lactation 8) Body Mass index more than 35 kg per metre square
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess and compare the analgesic efficacy of epidural nefopam versus tramadol in patients undergoing lower abdominal surgeries using Visual Analog Scale (VAS) pain score.Timepoint: 1st, 2nd, 4th, 6th, 12th ,24th hour | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the incidence and severity of adverse effects associated with epidural nefopam and tramadolTimepoint: upto first 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactDr Mancy ChristabelS
Vinayaka Missions Medical College and Hospital
Outcome results
None listed