FindTrial
Sign In

A study to see whether yoga or physical exercise helps to improve memory and thinking in older adults undergoing major surgery

Enhancing Cognitive functionality in Elderly Population Undergoing Major Surgery under General Anaesthesia: A comparative study of Yoga and Physical Prehabilitation Methods - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095841
Enrollment
200
Registered
2025-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F05- Delirium due to known physiological condition

Interventions

Intervention1: Yoga: Five yoga session of 60 minutes each will be conducted for 6 weeks. anulom-vilom pranayama (10 min), udgith pranayama (10 min), nadi shodhana pranayama (10 min), sheetali pranayam

Sponsors

Dr. Puneet Khanna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients Age above 60 years. 2. Undergoing major surgery under General Anaesthesia 3. ASA I and ASA II. 4. Fried Frailty Index more than 1 5. There is no minimum cognitive performance required to participate 6. Can give informed consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
1. To compare the effect of yoga-based prehabilitation and traditional physical prehabilitation in reducing the occurrence of POD in patients undergoing general major surgery. 2. To evaluate and compare the impact of yoga-based prehabilitation and physical prehabilitation on the incidence and severity of POCD in patients undergoing general major surgery. Timepoint: 1. Before Intervention 2. 24 hours before surgery 3. 24 hours after surgery 4. 8 weeks after surgery—

Secondary

MeasureTime frame
1. To evaluate the association between specific biomarkers (BDNF, MDA, CRP, TNF-alpha, dopamine, and noradrenaline) and the incidence of POCD and POD in patients participating in yoga-based prehabilitation versus traditional physical prehabilitation.Timepoint: 1. Before Intervention 2. 24 hours before surgery 3. 24 hours after surgery 4. 8 weeks after surgery—

Countries

India

Contacts

Public ContactDr Puneet Khanna

All India Institute of Medical Sciences, New Delhi

k.punit@yahoo.com9873106516

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026