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A study testing if adding a small dose of steroid medicine makes anaesthesia for children s lower-body surgeries work better and last longer

Efficacy of caudal block with or without Dexamethasone as an adjuvant by using perfusion index as an indicator in paediatric patients undergoing infra-umbilical surgeries- A Randomized double-blind, controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095765
Enrollment
70
Registered
2025-10-09
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: 1 ml/kg of 0.125% Bupivacaine with 0.1 mg/kg Dexamethasone: Group D: Patients will receive caudal block with local anaesthetic 0.125% bupivacaine 1ml/kg and dexamethasone (0.1 mg/kg to

Sponsors

Dr Shreja Saha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists (ASA) physical status I, II and III 2. Age- 2 -10 yrs patients 3. Posted for elective infra umbilical surgeries (e.g., inguinal hernia repair, orchidopexy, circumcision, lower limb procedures) requiring caudal block.

Exclusion criteria

Exclusion criteria: 1. Suspected coagulopathy 2.Patients with severe peripheral vascular disease, Raynauds disease, or poor peripheral circulation. 3. Known allergy to drugs used in the study 4. Patients with infection at the site of caudal block, sacral bone abnormalities.

Design outcomes

Primary

MeasureTime frame
Change in perfusion index (PI) after caudal blockTimepoint: baseline value, intraoperatively in intervals of 15 minutes and postoperatively at intervals of 3 hours, 6 hours, 9 hours and 12-hour.

Secondary

MeasureTime frame
Assess change in intraoperative heart rate, Blood pressure and Spo2 after caudal blockTimepoint: Intraoperatively every 15 mins and postoperative hemodynamic changes and postoperatively at intervals of 3 hours, 6 hours, 9 hours and 12-hours.;Post operative pain is observed using Face Pain ScaleTimepoint: At intervals of 3 hours, 6 hours, 9 hours and up to 12 hours

Countries

India

Contacts

Public ContactDr Sapna Das

Kalinga Institute Of Medical Sciences

gasdoc2001@yahoo.com8779478574

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026