Health Condition 1: K03- Other diseases of hard tissues ofteeth
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients requiring bilateral posterior mandibular complete crowns. 2.Teeth selected for temporary CAD/CAM milled and printed crown preparation should be restorable with a minimum crown to root ratio of at least 1:1. 3.Patients with good oral hygiene and periodontal status. 4.Patients with full complement of teeth . 5.Patients who will be available for the required follow up period. 6.Patients giving positive informed consent. 7.Patients with plaque index less than15%,bleeding index less than 10%.
Exclusion criteria
Exclusion criteria: 1.Patients with developmental defects of enamel and dentin 2.Patients with systemic disease(e.g., diabetic mellitus,,hypertension,cancer,sjogren, s syndrome etc.) 3.Habitual tobacco smokers or chewers. 4.Untreated gingival or periodontal disease 5.Parafunctional habits like bruxism, clenching. 6.Temporomandibular joint disorders. 7.Patients with fluorosis, calcium metabolic disorders, osteoporosis. 8.Patients having malocclusion . 9.Pregnant and breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1). To evaluate the level of IL-6 in gingival crevicular fluid(GCF) just before tooth preparation(baseline) and after cementation of CAD/CAM milled and 3D printed PMMA resin provisional crown on mandibular first molar at 2 week and 6 week . 2). To evaluate the level of IL-1 beta in gingival crevicular fluid(GCF) just before tooth preparation(baseline) and after cementation of CAD/CAM milled and 3D printed PMMA resin provisional crown on mandibular first molar at 2 week and 6 week. Timepoint: before preparation,after2 weeks and 6 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1). To compare the level of IL-6 in gingival crevicular fluid before tooth preparation (baseline)and after cementation of CAD-CAM milled and 3D printed provisional restoration on mandibular first molar at 2week and 6 week interval. 2). To compare the level of IL-1 beta in gingival crevicular fluid before tooth preparation (baseline)and after cementation of provisional restoration on mandibular first molar at 2week and 6 week interval. Timepoint: before preparation,after2 weeks and 6 weeks | — |
Countries
India
Contacts
CDER,AIIMS NEW DELHI.