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Comparative evaluation of cataract surgery combined with glaucoma surgery with or without Microhook ab interno Trabeculotomy in Primary angle closure glaucoma A pilot randomized controlled trial

Comparative evaluation of phacoemulsification combined with goniosynechialysis with or without Microhook ab interno Trabeculotomy in Primary angle closure glaucoma A pilot randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095716
Enrollment
64
Registered
2025-10-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H40-H42- Glaucoma Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical Health Condition 4: H402- Primary angle-closure glaucoma

Interventions

Intervention1: phacoemulsification, goniosynechialysis, Microhook ab interno Trabeculotomy: In Phaco-GSL + Microhook group, side port incisions (0.9 mm) with a standard temporal 2.2-mm clear corneal.
straight microhooks for nasal angles and right and left angled for temporal angles by gently sliding the tip into the SC rather than stabbing it in. Reaching the appropriate depth with the tip of
how well is the Schlemm s canal deroofed. A minimal resistance felt while probing the Schlemm s canal indicates that the depth is adequate and there has been no inadvertent damage to inner wall of SC.

Sponsors

Dewang Angmo
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Primary Angle Closure disease patients with cataract (who received laser peripheral iridotomy at least 8 weeks before) Age more than or equal to 40 years Patients willing to give consent

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
To compare the reduction in IOP in PhacoGSL+Microlot (PGM) vs PhacoGSL(PG) in PACDTimepoint: To compare the reduction in IOP in PhacoGSL+Microlot (PGM) vs PhacoGSL(PG) in PACD at baseline with day 1, 1 week, 4 weeks, 3 months, 6 months, 12 months—

Secondary

MeasureTime frame
To compare Reduction in number of anti glaucoma medications BCVA Post operative complications Change in angle parameters on ASOCT Correlation of ITC with gonioscopic findings & final reduction in IOP compare postoperative incisional cross-sectional area & correlate with IOP reduction TM tissue will be sent for scanning electron microscopy analysis whenever possible. Timepoint: at baseline with day 1, 1 week, 4 weeks, 3 months, 6 months, 12 months—

Countries

India

Contacts

Public ContactROHAN SUNIL SONAWANE

AIIMS, NEW DELHI

dewang45@gmail.com01126594127

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026