Health Condition 1: K806- Calculus of gallbladder and bile duct with cholecystitis Health Condition 2: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere
Conditions
Interventions
Intervention1: Intranasal Dexmedetomidine versus Intranasal Butorphanol in attenuation of haemodynamic response during laryngoscopy and intubation.: Haemodynamic response during laryngoscopy & intubat
Sponsors
Post Graduate Institute of Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: 1. ASA I/II 2. Either sex 3. 18 to 60 years of age 4. Elective general surgeries under general anaesthesia
Exclusion criteria
Exclusion criteria: 1. Patients not willing to participate in study 2. Any allergy to study drugs 3. Patients having comorbidities like cardiac disease & another organ dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of hemodynamic response (HR, BP) between the two groups during laryngoscopy and intubation. Timepoint: During laryngoscopy and intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Objectives: 1. To compare the adverse effects of both the drugs when administred via intranasal route. 2. To compare the dose reduction of IV induction agent i.e. propofol during induction of general anaesthesia. 3. To compare the MAC reduction of inhalational anaesthetics by observing haemodynamics of patient during surgery. 4. To compare sedation via Ramsay sedation score before induction & after extubation. 5. To compare VAS score after extubation. 6. Time to first rescue analgesia. Timepoint: During Perioperative period | — |
Countries
India
Contacts
Public ContactSAHIL GARG
PGIMER, Satellite Centre, Sangrur (Pb)
Outcome results
None listed