This study checks which numbing injection works best for dental treatment of the tooth nerve (vital pulp therapy) â?? Articaine, Bupivacaine, or Lidocaine

Assessment of anesthetic efficacy of Buccal infiltration with 4 percent Artcaine , 0.5 percent Bupivacaine and 2 percent Lidocaine Inferior Alveolar Nerve Block in Vital Pulp Therapy A Randomized Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/095699

Enrollment

Registered

2025-10-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified Health Condition 2: K029- Dental caries, unspecified

Interventions

Intervention1: 4 percent Articaine 0.5 percent bupivacaine: buccal infiltration with 0.8 ml of 4 percent articaine and 0.8 ml of 0.5 percent bupivacaine in vital pulp therapy. Study will be conducte

Eligibility

Inclusion criteria

Inclusion criteria: 1)Permanent first and second mandibular molars indicated for vital pulp therapy will be selected based on clinical and radiographic screening. 2)Hot tooth 3)Age group 12-16 years 4)Pulp involved vital tooth 5)ASA I

Exclusion criteria

Exclusion criteria: 1)Teeth with abscess , fistula, With swelling 2)RC treated 3)Periapical lesion 4)Furcation involved 5)Patient allergic to LA 6)Systemically compromised and patients with history of drug allergy ASA II ASA III 7)Children / Guardian who are not willing

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study is satisfactory anesthetic efficacy with 4% Articaine , 0.5% Bupivacaine and IANB with 2% lignocaineTimepoint: Pain is evaluated peroperative before starting procedure by patient heft parker visual analog scale HP VAS , during treatment Sound eye motor SEM will be recorded on caries excavation reaching deep dentine and /or pulp , after completion of procedure patient will be asked to record facial image scale ,heft parker visual analog scale study will be conducted in single visit appointment of patient assessment will be done intraoperatively and Postoperatively within one hour of time period	—

Measure

Time frame

The primary outcome of the study is satisfactory anesthetic efficacy with 4% Articaine , 0.5% Bupivacaine and IANB with 2% lignocaineTimepoint: Pain is evaluated peroperative before starting procedure by patient heft parker visual analog scale HP VAS , during treatment Sound eye motor SEM will be recorded on caries excavation reaching deep dentine and /or pulp , after completion of procedure patient will be asked to record facial image scale ,heft parker visual analog scale study will be conducted in single visit appointment of patient assessment will be done intraoperatively and Postoperatively within one hour of time period

—

Secondary

Measure	Time frame
post operative complication at site of injectionTimepoint: after 24 hours through telephonic communication	—

Countries

India

Contacts

Public ContactDr Hetal Joshi

JMFS ACPM DENTAL COLLEGE SAKRI ROAD DHULE

sandesh.bansal@gmail.com9689141996

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026