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A study comparing two methods of measuring breathing effort in patients to find the more accurate approach

Comparison and correlation between occlusion pressure with diaphraghmatic thickening fraction versus occlusion pressure with diaphraghmatic excursion in predicting successful extubation in critically ill patients - A Randomized clinical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095695
Enrollment
50
Registered
2025-10-08
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J22- Unspecified acute lower respiratory infection

Interventions

Intervention1: OCCLUSION PRESSURE: P0.1(Airway occlusion pressure) is the static pressure generated by all inspiratory muscles against an occluded airway at 0.1s after the onset of inspiration. It is

Sponsors

Department of Critical Care Medicine
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients willing to give consent Respiratory failure with mechanical ventilation more than 24 hours The ability to tolerate spontaneous breathing trial for more than 1 hour

Exclusion criteria

Exclusion criteria: 1. Neuromuscular diseases or 2.Diaphragmatic paralysis and 3.Tracheostomized patients. 4.Recent thoracoabdominal surgeries, 5.Morbidly obese patients, 6.Hemodynamically unstable patients, 7.Hhigh positive end expiratory pressure (PEEP) and intrinsic PEEP.

Design outcomes

Primary

MeasureTime frame
To assess the correlation between the diaphragmatic thickness fraction , Diaphraghmatic excursion and P0.1 in the assessment of patients contribution in mechanical ventilation.Timepoint: 0,12,24 hours

Secondary

MeasureTime frame
Extubation success, duration of mechanical ventilation, length of ICU and hospital stays.Timepoint: days

Countries

India

Contacts

Public ContactDr Sathya Narayanan K

Bangalore Medical College and Research Institute, Bangalore - BANGALORE

viji2751977@gmail.com09597447444

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026