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Comparing the two medication gabapentin versus clonidine tablet for better post operative pain relief and duration in lower abdomen surgery

Comparison between oral gabapentin and oral clonidine premedication for post operative pain relief in patient undergoing lower abdomen surgery under spinal anaesthesia A randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095689
Enrollment
82
Registered
2025-10-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: tablet gabapentin 600 milli gram: Patient taken tablet orally 1 hour before administration of spinal anaesthesia with sips of water Control Intervention1: tablet clonidine 600 microgram

Sponsors

dr revaanth E R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patient willing to give informed written consent 2 Adult normotensive patients aged between 18 to 60 years posted for surgery 3 American society of Anaesthesiology grade 1 or 2

Exclusion criteria

Exclusion criteria: 1 Any contraindications for spinal anesthesia 2 Patients undergoing emergency surgical procedures 3 Patients on anti-hypertensives sedativies MAO-inhibitors tricyclic antidepressants opioids drugs Analgesic 4 Patients with neurological cardiac respiratory metabolic renal or hepatic disorders coagulation abnormalities 5 Patients has known allergy or hypersensitivity to drugs 6 Patient with history of pre-operative bradycardia hypotension Pregnant women psychiatric illness 7 Patients who refused to participate were excluded from the study

Design outcomes

Primary

MeasureTime frame
To compare the duration of post operative AnalgesiaTimepoint: 2nd, 4th 6th 8th 12th 24th hours—

Secondary

MeasureTime frame
To compare the duration of sensory and motor subarachnoid block Assessment of sedation by Ramsay sedation score To look for other side effects like Hypotension Bradycardia drowsiness dizziness Nausea and Vomiting Timepoint: 2nd, 4th 6th 8th 12th 24th hours—

Countries

India

Contacts

Public Contactdr ramachandraiah r

Bangalore medical college and research institute

Kanikekeerthi1438@gmail.com9663870054

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026