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Outcome of Metabolic resucuitation:HAT Therapy in patients of SAM with Sepsis/Septic Shock.

Outcome of Hydrocortisone,Ascorboc Acid and Thiamine therapy in patients of Severe Acute Malnutrition with Sepsis or Septic shock. - nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095645
Enrollment
80
Registered
2025-10-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E46- Unspecified protein-calorie malnutrition

Interventions

Intervention1: Injection Hydrocortisone,Ascorbic Acid and Thiamine Therapy .: IV Hydrocortisone 1mg/kg/dose in slow bolus 6 hourly. IV Ascorbic Acid 30 mg/kg/dose every 6 hourly over 30-60 minutes. I

Sponsors

Amulya Pandey
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All patients Fulfilling the Sam Criteria of weight by height less than 3 standard deviation ,Mid upper arm circumference less than 115cm or Bilateral Pedal Oedema.

Exclusion criteria

Exclusion criteria: Renal Failure ,Hepatic Failure ,other causes of Shock (hypovolemic,haemorrhagic,cardioigenic and neurogenic),Metabolic disorders,Chemotherapy/Steroid Therapy patients.

Design outcomes

Primary

MeasureTime frame
Outcome of Hydrocortisone Ascorbic Acid and thiamine therapy in patients of sam with sepsis /septic shock. Pheonix sepsis score and fss score assessed.Timepoint: At 0 ,3 and 7 days after admission.

Secondary

MeasureTime frame
Effectiveness of HAT therapy in recovery from septic shock assessed in terms of Number and duration of inotrope requirement Duration of Invasive & Non Invasive Mechanical Ventilation Duration required for reversal of septic shock Duration of stay in PICU Duration of Hospital stay Survival and mortality percentages of both treatment groups Timepoint: 28 days

Countries

India

Contacts

Public ContactDr Karan Joshi

SHYAM SHAH MEDICAL COLLEGE

drkaranjoshi65@gmail.com94251849756

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026