Health Condition 1: 3- Administration
Conditions
Interventions
Intervention1: Tapentadol hydrochloride: 45 mg intrnasally 30 minutes before extubation
Control Intervention1: Tramadol hydrochloride: 1 mg/kg body wt intravenously 30 minutes before extubation
Sponsors
Dr Sourangshu Biswas
Eligibility
Inclusion criteria
Inclusion criteria: ASA I/II patients undergoing elective cholecystectomy patients wiling to provide informed consent
Exclusion criteria
Exclusion criteria: ASA III or IV History of bronchial asthma History of hypersensitivity to the study drugs Patients having any intranasal pathology Patients requiring nasal intubation Serum creatinine more than 2 mg percent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score on visual analog scale Timepoint: at 0 minute following extubation, at the end of 30th minute, 1st hour,2nd hour,4th hour, 6th hour and 12th hour in the post operative period | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation score using Ramsay sedation score scale Timepoint: at 0 minute following extubation at the end of 30th minute at the end of 1st hour 2nd hour 4th hour 6th hour & 12th hour in the post operative period;Nausea & vomiting severity scoreTimepoint: at 0 minute following extubation at the end of 30th minute at the end of 1st hour 2nd hour 4th hour 6th hour & 12th hour in the post operative period | — |
Countries
India
Contacts
Public ContactDr Tirthasish Mandal
Burdwan Medical College and Hospital
Outcome results
None listed