A Study Comparing Pain Relief After Breast Augmentation Surgeries Using Ultrasound Guided Nerve Block With Ropivacaine Combined Either With Dexmedetomidine Or With Nalbuphine.

Comparison Of Postoperative Analgesic Efficacy Of 0.5 Percentage Ropivacaine With Dexmedetomidine Versus 0.5 Percentage Ropivacaine With Nalbuphine In Ultrasound Guided Erector Spinae Plane Block For Breast Augmentation Surgeries A Prospective Randomized Double Blinded Study - NIIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/10/095633

Enrollment

100

Registered

2025-10-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ropivacaine with Dexmedetomidine and Ropivacaine with Nalbuphine: Drug Ropivacaine 0.5% + Dexmedetomidine 1 mcg per kg Route Ultrasound guided ESP block at level of T3. Total Volume 35

Eligibility

Inclusion criteria

Inclusion criteria: Patients under ASA Physical Status I and II undergoing breast augmentation surgery Plastic Surgery. Gender Transgender patients. Patients with BMI between 20 to 30 kg per m .

Exclusion criteria

Exclusion criteria: Severe spinal deformity. Known allergy to local anaesthetics. Systemic illnesses such as uncontrolled hypertension, diabetes, seizure disorder, cardiopulmonary disease. Bleeding disorders, block site infection, hepatic or renal dysfunction. BMI more than 30 kg per m . Patients on anticoagulants/blood thinners. History of head injury. Psychiatric illness.

Design outcomes

Primary

Measure	Time frame
Duration of postoperative analgesia measured as the time interval between administration of ESP block and first rescue analgesic requirement, recorded in minutes or hours within 24 hours post surgery.Timepoint: Duration of postoperative analgesia measured as the time interval between administration of ESP block and first rescue analgesic requirement, recorded in baseline , 12th hr and 24th hr post surgery.	—

Measure

Time frame

Duration of postoperative analgesia measured as the time interval between administration of ESP block and first rescue analgesic requirement, recorded in minutes or hours within 24 hours post surgery.Timepoint: Duration of postoperative analgesia measured as the time interval between administration of ESP block and first rescue analgesic requirement, recorded in baseline , 12th hr and 24th hr post surgery.

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactMohammed Asjad T

Shri Sathya Sai Medical Collgege And Research Institute.

drasjad97@gmail.com9894967243

Outcome results