Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Group N - Nebulization with dexamethasone: Upon arrival in the preoperative room, the patients will receive nebulization with a 5 ml solution for 15-20 minutes and intravenous injection
Sponsors
Dr Sunaina Tejpal Karna
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anesthesiologists physical status (ASA) I & II Patients undergoing Spine surgery in the prone position under General anaesthesia with endotracheal intubation with an armoured tube Providing written informed consent for study participation
Exclusion criteria
Exclusion criteria: Cervical spine surgery Pregnant or breastfeeding females Patients already on steroid therapy or having taken steroids in any form 12 hours before surgery Patients with ongoing sore throat or pain in the throat or asthma or hoarse voice or history of respiratory tract infection or sore throat in the 2 weeks before surgery Diabetes mellitus Immunocompromised patients Impaired renal cardiac or hepatic function Patient with psychiatric disorders or antipsychotic therapy Allergy to Dexamethasone More than three attempts are required for intubation The patient needs postoperative mechanical ventilation in the intensive care unit
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Postoperative sore throat (POST) between both the groupsTimepoint: At 2, 6, 12, and 24 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Grade of POST on a 4-point scale in between both the groupsTimepoint: at 2, 6, 12, and 24 hours after surgery;Incidence of hoarseness of voice, dysphagia, stridorTimepoint: At 2,6, 12, 24 hours after surgery;Incidence of postoperative nausea and vomiting atTimepoint: At 2, 6, 12, 24 hours after surgery;Quality of recovery with QoR-15 scoreTimepoint: At 48 hours and 1 week after surgery | — |
Countries
India
Contacts
Public ContactSunaina Tejpal Karna
AIIMS Bhopal
Outcome results
None listed