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Study comparing one versus two ultrasound-guided injections for carpal tunnel syndrome

Comparative analysis of single versus double injection ultrasound-guided perineural hydrodissection of the median nerve in carpal tunnel syndrome: a randomised controlled trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095537
Enrollment
74
Registered
2025-10-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G560- Carpal tunnel syndrome

Interventions

Intervention1: Group B (Double injection): Participants in this group will receive two ultrasound-guided injections of 10 mL of 5% dextrose around the median nerve in carpal tunnel, with the second in

Sponsors

Anjali Kumari
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Clinical diagnosis of mild to moderate CTS (based on symptoms, nerve conduction study and median nerve cross-sectional area on ultrasound examination) Symptom duration more than 3 months Able to provide informed consent

Exclusion criteria

Exclusion criteria: Previous carpal tunnel surgery Severe CTS (denervation changes on EMG) Other upper limb neuropathies or thoracic outlet syndrome, cervical radiculopathy or brachial plexopathy Coagulopathy or anticoagulant use Previous corticosteroid injection in the affected wrist within 6 months Pregnancy or lactation Systemic diseases such as thyroid disorders, rheumatoid arthritis, diabetes mellitus, chronic renal failure

Design outcomes

Primary

MeasureTime frame
Pain score as measured by numerical pain rating scale (NRS)Timepoint: At baseline, 4, 12, and 24 weeks

Secondary

MeasureTime frame
Boston carpal tunnel syndrome questionnaire symptom severity score (BCTQ SSS)Timepoint: At baseline, 4, 12, and 24 weeks;Median nerve cross-sectional area at pisiform level on ultrasonographyTimepoint: At baseline, 4, 12, and 24 weeks;Patient satisfaction (Likert scale)Timepoint: At 4, 12, and 24 weeks;Nerve conduction study parameters (distal motor latency, sensory latency, sensory conduction velocity)Timepoint: At baseline and 24 weeks

Countries

India

Contacts

Public ContactAnjali Kumari

Kalinga institute of medical sciences, Bhubaneshwar

anjali.kumari@kims.ac.in9007474943

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026