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Comparing different doses and schedules of oral isotretinoin treatment for people with acne.

COMPARATIVE STUDY OF ORAL ISOTRETINOIN AS CONVENTIONAL, INTERMITTENT AND LOW DOSE REGIMEN IN MANAGEMENT OF ACNE VULGARIS. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/10/095515
Enrollment
72
Registered
2025-10-01
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L700- Acne vulgaris

Interventions

Intervention1: Comparative study of oral isotretinoin as low dose regimen in management of acne vulgaris.: 72 group of patients will be divided into 3 groups who meet all the inclusion criteria and wi

Sponsors

Dr Saoji Ojasvi Virendra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with failure of first-line therapy. Moderate to severe acne frequently relapsing Moderate acne with imminent scarring Severe acne with nodules and cysts Inflammatory acne with scarring Patients who are married and not planning for pregnancy are advised to use contraceptives.

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA: 1 Age less than 18 years. 2 Pregnancy, married females planning for pregnancy. 3 Drug-induced acne. 4 Abnormal liver functional tests, h/o Hyperlipidemia. 5 Musculoskeletal deformity.

Design outcomes

Primary

MeasureTime frame
To compare the conventional, intermittent and low dose regimens of oral Isotretinoin in terms of efficacy, side effects and compliance. To evaluate the recurrence rates associated with Isotretinoin treatment regimensTimepoint: Done at baseline, 4 weeks & 8 weeks.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Gopalakrishnan

Chettiand Hospital and Research Institute

dermdrgopalakrishnan@gmail.com09884070883

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026