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Comparing Two Different Tests to Detect Glaucoma Early in People Who May Have It

Comparative analysis of Nasal Step Threshold versus 24-2 Humphrey Field Analyser field testing in diagnosis of glaucoma among glaucoma suspects - nil

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095457
Enrollment
86
Registered
2025-09-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H40- Glaucoma Health Condition 2: H400- Glaucoma suspect

Interventions

Intervention1: Nasal Step Threshold Visual Field Testing on Humphrey Field Analyser (HFA): The intervention in this study is the use of the Nasal Step Threshold Test ie NSTT, which is a testing regime

Sponsors

Dev Charan
Lead Sponsor
Department of Ophthalmology Kasturba Medical College Manipal
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age more than 18 years 2. Both genders 3. Disease Condition: Glaucoma suspects. Glaucoma suspects were defined as those with ANY ONE OR MORE of the following features: -Individuals with elevated intraocular pressure , that is, beyond 21mmHg. -Individuals with manifest optic disc changes, such as Optic Disc Cupping, Neuroretinal Rim Thinning, or Loss. or retinal nerve fiber layer abnormalities, as seen by standard of care testing. -Individuals with risk factors such as strong positive family history of glaucoma

Exclusion criteria

Exclusion criteria: 1. Individuals with unreliable visual field testing results. 2. Those with a best corrected visual acuity worse than 6 by 18. 3. Those not capable of sitting upright. 4. Those with other ocular diseases affecting visual fields, such as retinal detachment, central vein occlusion, diabetic retinopathy or other neuropathies unrelated to the study condition. 5. History of intraocular surgery, other than uncomplicated cataract or glaucoma surgery.

Design outcomes

Primary

MeasureTime frame
-Sensitivity and Specificity of Nasal Step Threshold Test and 24-2 testing in the diagnosis of Glaucoma among Glaucoma suspectsTimepoint: Across follow up as advised for glaucoma screening, such as at 3 months, 6 months and 1 year across follow up visits.

Secondary

MeasureTime frame
-Comparison of nature & absolute number of VF changes (eg step defects) picked up by the two tests -Descriptive analysis of field changes in both, which can be quantified as a set of testing criteria for Nasal step defects as seen in BOTH 24-2 AND NSTT -Comparison of time taken for both.Timepoint: Across follow up as advised for glaucoma screening, such as at 3 months, 6 months & 1 year across follow up visits.

Countries

India

Contacts

Public ContactDr Dev Charan

Department of Ophthalmology, Kasturba Medical College, Manipal

neetha.kir@manipal.edu9886161979

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026