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Comparison of three different methods- nebulisation with Dexmedetomidine, Inj Dexamethasone intravenously and intra-cuff Lignocaine, for the prevention of sore throat in the postoperative period for patients undergoing surgeries under general anaesthesia.

Comparison of Nebulized Dexmedetomidine, Intravenous Dexamethasone and Intra-cuff Lignocaine for Prevention of Postoperative Sore Throat: A Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095450
Enrollment
105
Registered
2025-09-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulization with Dexmedetomidine: Nebulization with dexmedetomidine given 15 min before induction of anaesthesia. Control Intervention1: Intravenous Dexamethasone: Dexamethasone 8mg IV

Sponsors

SRM Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA PS 1 and 2 Patients undergoing elective surgeries under general anaesthesia with endotracheal intubation Duration of surgery more than one hour Normal BMI

Exclusion criteria

Exclusion criteria: Patients with history of respiratory diseases or Diabestes History of smoking in last one week Allergy to local anaesthetic agent Surgeries in prone position Patient refusal

Design outcomes

Primary

MeasureTime frame
Incidence and severity of post operative sore throatTimepoint: Assessed at 2, 6, 12 and 24 hours in the postoperative period—

Secondary

MeasureTime frame
Incidence of postoperative nausea and vomitingTimepoint: Upto 12 hours in postoperative period;Intraoperative blood Pressure and Heart rate monitoringTimepoint: Monitored at 15 minute intervals intraoperatively—

Countries

India

Contacts

Public ContactVenkatraman R

SRM Medical College Hospital and Research Center

drvenkat94@gmail.com9894581455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026