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To compare Amisulpride and Ondansetron for Postoperative Nausea and Vomiting prophylaxis in patients undergoing laparoscopic cholecystectomy.

Amisulpride over Ondansetron for Postoperative Nausea and Vomiting prophylaxis: A double blind Randomized control study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095445
Enrollment
66
Registered
2025-09-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: AMISULPRIDE 5mg: Amisulpride 5 mg single dose intravenous route of adminstration was given 30 minutes before extubation and patient was observed for 24 hours for postoperative nausea an

Sponsors

Dr Aman Mathur
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients belonging to ASA 1 and ASA 2 category 2. Patients willing to give written informed consent 3. Patients with APFEL score 2 or more than 2.

Exclusion criteria

Exclusion criteria: 1. Patient who received any additional drug or intervention along with the standardized anesthesia procedure during surgery. (Patients whose anesthesia procedure is deviated from routine institutional protocol.) 2. Patients with known allergy to study drugs. 3. Pregnant and lactating mothers. 4. Known psychiatric disorder on antipsychotic drugs.

Design outcomes

Primary

MeasureTime frame
To compare antiemetic action of Amisulpride with Ondansetron.Timepoint: 3,6,12,24 hours post operatively.

Secondary

MeasureTime frame
To assess the patient post operatively for any side effects.Timepoint: 3,6,12,24 hours post operatively

Countries

India

Contacts

Public ContactParamanand Maheshwari

N F Railway Central Hospital

drpmaheshwari@gmail.com9435150509

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026