Effect of ketamine infusion on fentanyl consumption in patients undergoing lumbar fixation surgery.

Assessment of Effect of Ketamine on intraoperative opioid consumption in Patients undergoing Lumbar Fixation Surgery using Surgical Pleth Index: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095442

Enrollment

Registered

2025-09-29

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ketamine: Ketamine infusion during surgery to see intraoperative fentanyl consumption in lumbar fixation surgery. Control Intervention1: 0.9% Normal saline: 0.9% normal saline infusion

Eligibility

Inclusion criteria

Inclusion criteria: 1. Males or Females 2. Age: 18-75 years 3. ASA physical status I-II (American Society of Anaesthesiology)

Exclusion criteria

Exclusion criteria: 1. Patients with cardiac rhythm disorders, pacemakers, sympathetic nerve stimulators, vagus nerve stimulators. 2. Patients who underwent sympathectomy, vagotomy. 3. Patients on anti depressant, anti-anxiety, anticonvulsant and anti-parkinsonian drugs. 4. Known alcohol/ substance abuse. 5. Failure to obtain consent.

Design outcomes

Primary

Measure	Time frame
Cumulative fentanyl consumptionTimepoint: intraoperatively every 15 minutes	—

Secondary

Measure	Time frame
Recovery timeTimepoint: From skin closure to tracheal extubation;Post operative pain scores and requirement of rescue analgesiaTimepoint: At 30 min, 2hr, 6hr, 12hr and 24hr after surgery;Post operative nausea and vomitingTimepoint: At 30min, 2hr, 6hr, 12hr and 24 hr after surgery	—

Countries

India

Contacts

Public ContactDr Partiksha Jakhar

Sir Ganga Ram Hospital, New Delhi

drneetujain@yahoo.com9871110160

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026