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An observational study to Assess the Use of Blood Markers Prolactin and Creatine Phosphokinase levels in Distinguishing Epileptic Seizures from Non-Epileptic Events

Evaluating Serum Prolactin and Creatine Phosphokinase as Differential Biomarkers in Epileptic Versus Psychogenic Non-Epileptic Seizures - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/09/095432
Enrollment
46
Registered
2025-09-26
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil

Sponsors

Roshan M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with confirmed Epileptic Seizures aged above 18 years based on clinical history and video-EEG findings. Patients with confirmed Psychogenic Non-Epileptic Seizures aged above 18 years based on video-EEG and absence of epileptiform activity.

Exclusion criteria

Exclusion criteria: Presence of other neurological disorders where CPK is elevated. History of substance abuse. Post-traumatic injury associated with Intracranial meningioma, Lactate dehydrogenase, and pregnancy due to increased prolactin.

Design outcomes

Primary

MeasureTime frame
To assess and compare serum Prolactin levels in patients diagnosed with Epileptic Seizures and patients diagnosed with Psychogenic Non-Epileptic Seizures following a witnessed event.Timepoint: To assess and compare serum Prolactin levels in patients diagnosed with Epileptic Seizures and patients diagnosed with Psychogenic Non-Epileptic Seizures following a witnessed event.—

Secondary

MeasureTime frame
To evaluate the potential for a combined analysis of Prolactin & Creatine Phosphokinase levels to improve the accuracy of differentiating Epileptic Seizures from Psychogenic Non-Epileptic Seizures compared to either biomarkerTimepoint: To compare prolactin & CPK levels after seizure within 30 minutes occurrence—

Countries

India

Contacts

Public ContactDr Salma Suhana

Yenepoya Medical college Hospital

suhanas18@gmail.com9741967190

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026