Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Antiemetic will be given preoperatively: 1 h before surgery
Control Intervention1: Oral pyridoxine tablet: 1 h prior to surgery in group PO
Control Intervention2: Group NO: No drug will
Sponsors
UCMS and GTB Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Consenting ASAI/II adult females Undergoing laparoscopic surgery Requiring general anesthesia
Exclusion criteria
Exclusion criteria: Pregnant patient, Patient with cardiac, hepatic and renal disease and known case of tuberculosis Developmental delay, mental illness, severe neurological disease Allergic to any drug used in study Long term use of long-acting antiemetic, emetogenic drugs, opoids, glucocorticoids or cancer therapy and add on any antiemetic in last 24 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post operative nausea vomiting(PONV) in first 24 hour after surgeryTimepoint: Postoperative- 0-2 hour, 2-6 hour, 6-12 hour, 12-24 hour | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to first occurrence of PONV Severity of PONV Requirement of rescue antiemetic drugs Side effects, if anyTimepoint: Intraoperative- 15 min, 30 min, 60min, 90 min, 120 min, 150 min, 180 min, 210 min Postoperative- 0-2 hour, 2-6 hour, 6-12 hour, 12-24hour | — |
Countries
India
Contacts
Public ContactDr Sakshi
University College of Medical Sciences and GTB Hospital, Delhi
Outcome results
None listed