Comparing new therapies with regular dental cleaning procedure.

Comparative evaluation of the adjunctive use of ozone therapy, antimicrobial photodynamic therapy and topical oxygen-releasing gel compared to scaling and root planing alone: a single blinded randomized controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095387

Enrollment

120

Registered

2025-09-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Adjunctive periodontal therapy- ozone therapy.: Group A will receive scaling and root planing (SRP) followed by subgingival ozone therapy. Intervention2: Adjunctive periodontal therapy-

Eligibility

Inclusion criteria

Inclusion criteria: Participants diagnosed with moderate to severe periodontitis will be included. Eligible individuals must have at least 16 teeth, with a minimum of four teeth present in each quadrant. Participants should be between 18 and 65 years of age.

Exclusion criteria

Exclusion criteria: History of antibiotic use within the previous 6 months. History of periodontal therapy within the last 12 months. Presence of uncontrolled systemic diseases. Presence of respiratory diseases. Current daily smokers. Pregnant or lactating women. Presence of cervical caries or cervical restorations. Ongoing orthodontic therapy.

Design outcomes

Primary

Measure	Time frame
Reduced probing depthTimepoint: At baseline, 6 weeks, 4 months, 6 months	—

Secondary

Measure	Time frame
relative attachment levelTimepoint: 6 weeks, 4 months, 6 months	—

Countries

India

Contacts

Public ContactDr Nayana Patel

Government Dental College and Hospital, Jamnagar

drnayanagpatel@gmail.com9825191911

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026