Health Condition 1: L430- Hypertrophic lichen planus
Conditions
Interventions
Intervention1: Oral TOFACITINIB: 5mg,BD per oral for 3 months
Control Intervention1: Oral Methotrexate: 10mg weekly once per oral for 3 months.
Sponsors
Maharajahs institute of medical sciences
Eligibility
Inclusion criteria
Inclusion criteria: All Patients between age of 18 to 60 yrs with clinical and Dermoscopic features suggestive of Lichen Planus. Patients of all genders. All the patients who give their consent to the study.
Exclusion criteria
Exclusion criteria: Special variants of LP like Mucosal LP,Lichen Planus pigmentosus, and Follicular LP. Patients who are already used topical therapy for last 2 weeks and systemic therapy for last 4 weeks for lichen Planus. Patients having abnormal Haematological parameters,LFT and RFT. Patients with active or past history of tuberculosis,Immunodeficiency states (HIV patients,those who were on immunosuppressants and corticosteroids). Pregnancy and lactation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decreased visual analog scale Increased patient satisfaction score will be assessed at baseline,4 weeks and 8 weeksTimepoint: Adverse effects will be noted at baseline,4 weeks and 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactSAMADHI JAYASREE SAILAKSHMI
Maharajahs institute of medical sciences
Outcome results
None listed