Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ASA I or II, with BMI between 25 and 30kg/m2, undergoing elective lumbosacral spine surgeries under general anaesthesia
Exclusion criteria
Exclusion criteria: Patients with known allergies to medications used in this study, patients undergoing long term pain management, patients with preexisting respiratory, renal, hepatic or cardiovascular conditions, patients with clotting disorders or coagulopathies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess postoperative pain intensity at rest and during movement and to assess time from isoflurane discontinuation to tracheal extubation and recovery timeTimepoint: 30 minutes, 2 hours, 4 hours, 8 hours,12 hours and 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes of the trial are - to measure time for first request of rescue analgesic (ketorolac) after surgery, to calculate total ketorolac consumption within first 24 hours postoperatively, to assess time of discharge from PACU (Post anaesthesia care unit), to evaluate incidence of postoperative side effects particularly nausea, vomiting & sedation during firt 24 hours postoperatively & to evaluate & compare the levels of inflammatory marker(C Reactive protein-CRP) in pre & postoperative periodsTimepoint: 24 hours postoperatively | — |
Countries
India
Contacts
Shri B. M. Patil medical college, hospital and research center