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comparing opioid-free anaesthesia with retrolaminar block versus conventional anaesthesia for faster recovery after lower back surgeries

A randomised clinical trial to compare the efficacy of opioid free anaesthesia with retrolaminar block and conventional anaesthesia method to know enhanced recovery in posterior lumbosacral surgeries - NIL

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095341
Enrollment
98
Registered
2025-09-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Retrolaminar block: General anaesthesia was induced using IV propofol 2 mg/kg and 0.5 g/kg dexmedetomidine over 10 min, and endotracheal intubation was facilitated with IV atracuriu

Sponsors

Dr Arya Srinivasan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I or II, with BMI between 25 and 30kg/m2, undergoing elective lumbosacral spine surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: Patients with known allergies to medications used in this study, patients undergoing long term pain management, patients with preexisting respiratory, renal, hepatic or cardiovascular conditions, patients with clotting disorders or coagulopathies

Design outcomes

Primary

MeasureTime frame
To assess postoperative pain intensity at rest and during movement and to assess time from isoflurane discontinuation to tracheal extubation and recovery timeTimepoint: 30 minutes, 2 hours, 4 hours, 8 hours,12 hours and 24 hours

Secondary

MeasureTime frame
Secondary outcomes of the trial are - to measure time for first request of rescue analgesic (ketorolac) after surgery, to calculate total ketorolac consumption within first 24 hours postoperatively, to assess time of discharge from PACU (Post anaesthesia care unit), to evaluate incidence of postoperative side effects particularly nausea, vomiting & sedation during firt 24 hours postoperatively & to evaluate & compare the levels of inflammatory marker(C Reactive protein-CRP) in pre & postoperative periodsTimepoint: 24 hours postoperatively

Countries

India

Contacts

Public ContactDr Arya Srinivasan

Shri B. M. Patil medical college, hospital and research center

shivanandkarigar82@gmail.com9164319345

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026