Comparison of Dexmedetomidine and Clonidine for Pain Relief and Sleep in Children After Caudal Anesthesia for Lower Abdominal Surgery

Comparison of Analgesic and Sedative effects of equipotent doses of Dexmedetomidine versus Clonidine as Adjuvants in Pediatric caudal Anesthesia under USG guidance technique- A Randomized control trial - Nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/09/095339

Enrollment

Registered

2025-09-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: 0.5 mcg/kg of Dexmedetomidine will be given in. Caudal epidural space. Control Intervention1: Clonidine: 0.5 mcg/kg given in caudal epidural space.

Eligibility

Inclusion criteria

Inclusion criteria: Patient undergoing elective infraumbilical surgeries ASA 1 and 2

Exclusion criteria

Exclusion criteria: Local infection, coagulopathy, spine deformity, allergy to study drugs

Design outcomes

Primary

Measure	Time frame
Mean arterial pressureTimepoint: 0,5, 10, 15, 30, 60, 90, 120, 150,180 minutes	—

Secondary

Measure	Time frame
FLACCTimepoint: 15, 30, 60, 90, 120, 150, 180 minutes, 6 hours, 12 hours, 24 hours;MRSSTimepoint: 15, 30, 60, 90, 120, 150, 180 minutes, 6 hours, 12 hours, 24 hours	—

Countries

India

Contacts

Public ContactDr Nagalaksmi P

Sri Manakula Vinayagar Medical College and Hospital, Kalitheerthalkuppam, Madagadipet, Puducherry

Vedha83@gmail.com9894510137

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026