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Studying the Use of Opioid-Free Anaesthesia in Heart Bypass Surgery Patients to Improve Recovery After Surgery

Opioid free anaesthesia for coronary revascularization surgery and its effect on post-operative recovery- An observational prospective study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/09/095276
Enrollment
30
Registered
2025-09-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj Dexmedetomidine, Inj Lidocaine, Inj Ketamine: Inj Dexmedetomidine 0.25 g/kg i.v is administered for 10min while securing central line and arterial line. A 50 ml solution containin

Sponsors

Academic Investigator Initiated study
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Good Left Ventricle Function Greater than 45 percentage Ejection Fraction. 2.No History of stroke, Central Nervous System disorders, any psychiatric medications 3.Adult patients 18 to 75 years old. 4.Scheduled for an elective Coronary Artery Bypass Graft. 5.Patient consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Reduced Left Ventricle function less than 45 percentage Ejection Fraction. 2.Known history of opioid abuse. 3.Bradycardia less than 50 beats per minute. Heart blocks greater than 2nd degree. 4.Contraindication to one of the trial drugs (dexmedetomidine, lidocaine, Magnesium sulphate, ketamine, non- steroidal anti- inflammatory drugs 5.Body mass index greater than or equal to 35 kg per meter square. 6.Combined cardiac surgeries other than aortic valve replacement. 7.Cognitive disorders. 8.Patients refusal consent.

Design outcomes

Primary

MeasureTime frame
To explore the efficacy of Opioid free anaesthesia in coronary vascularisation surgeries by assessing the quality of anesthesia, postoperative pain levels and adverse effects.Timepoint: At the end of study duration data will be collected study duration 12 months—

Secondary

MeasureTime frame
1.To assess the Haemodynamic response to intubation and surgery including incidence of bradycardia in the patients. 2.To assess the efficacy of the nerve blocks in terms of postoperative pain scores. 3.To monitor the depth of anaesthesia with BIS monitor. 4.Time taken for extubation. 5.overall patient satisfaction score. 6.Any adverse events. Timepoint: To explore the efficacy of Opioid free anaesthesia in coronary vascularisation surgeries by assessing the quality of anesthesia, postoperative pain levels and adverse effects.—

Countries

India

Contacts

Public ContactDr Geetha Muniraju

Fortis Hospital Limited

drgeethachetan@gmail.com8971099794

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026